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The liver is one of the most metabolically active organs, being involved in key digestive, metabolic and excretory activities. Its function can be altered when the animal is exposed to toxic compounds such as mycotoxins, which is more frequent in animals with long lifespans.
Aflatoxins are the best known hepatotoxic mycotoxins. Low levels of aflatoxins do not impair performance but reduce the concentration of albumin and total proteins in the blood, a sign that protein synthesis in the liver is negatively affected. At higher levels, aflatoxins induce hepatocyte damage, which results in necrosis or in cellular dysfunction.
Fumonisins interfere with the synthesis of sphingolipids. Sphingolipids are a class of lipids found in cell membranes, especially in tissues located in liver, lungs, heart, brain and nerves. The disruption of sphingolipid metabolism results in disturbances of cellular processes such as cell growth, differentiation, morphology, permeability and death. Hepatic injury is dose- and time-dependent.
Ochratoxin A induces liver inflammation and necrosis. The precise mechanism of toxicity is not yet known, but it is suspected to be related to oxidative stress.
T-2 toxin causes the death of the hepatocytes by producing reactive oxygen species (ROS) that lead to oxidative damage in the mitochondria.
Botanicals have been used traditionally for the prevention and treatment of liver diseases.
Clinical and basic scientific research have confirmed that some plant extracts can protect farm animals against the negative consequences of mycotoxins in the liver.
The mechanisms of action of hepatoprotective phytogenics are the following:
Phytogenics with hepatoprotective effects can be used routinely for the prevention of liver damage or to promote liver regeneration when animals have already been exposed to mycotoxins.
BioShield© is a complete solution that protects your animals against toxicity by mycotoxins. It includes:
PhytoLiv© is an oral emulsion that contains essential oils, bioactives and vitamins with high antioxidant power. PhytoLiv© is especially useful in the following cases:
PhytoMax© is a combination of vitamins, chelated calcium, microminerals and essential oils to be given through drinking water. It is intended for layers and breeders to:
Certain health statements may not be applicable in your region.